There are a variety of methods of testosterone replacement: injections, patches, creams, gels, sublingual troches, oral tablets and subcutaneous pellets. Injections are painful and have a roller-coaster effect. Patches are not user-friendly. Oral administration is harmful to the liver. Creams and gels have to be applied 1-2 times a day. Pellets are surgically inserted under the skin. None of these methods are as convenient as when the body produces its own testosterone, but not replacing testosterone to optimal levels is detrimental to one’s health. The two methods we prefer are transdermal creams and subcutaneous pellets. The transdermal cream is applied two times per day and the body receives a steady amount of testosterone as well, but the cream must be applied twice a day, every day. Once implanted, pellets deliver a steady dose of testosterone. Within 4-6 months the pellets have been depleted and more must be implanted.